Apple peel extract can delay the aging process

Apple peel extract can delay the aging process

July 17, 2018 Source: Science and Technology Daily Author: Feng Weidong

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"An apple a day, the doctor is away from you" is a familiar health proverb. However, the best way to eat apples is to eat them with skin. According to the latest issue of Nature Medicine, US researchers have found that the combination of dasatinib (a leukemia drug) and quercetin (a extract from apple skin) can extend the lifespan of older mice. 36%.

Aging cells usually appear in the human body in their 60s, but appear earlier in obese or chronically ill patients. These abnormal cells are in a state of decline, but they are not willing to die. Some people think that aging cells themselves can catalyze the aging process.

The research team led by James Kirkland of the Mayo Clinic in the United States has proved that this is indeed the case. When the researchers injected small amounts of senescent cells into 6-month-old mice, their speed, endurance, and strength dropped by 20% to 50% in a few weeks, almost the same level as a typical 2-year-old mouse.

To block the effects of aging cells, the team chose a combination of dasatinib and quercetin because both would interfere with the way aging cells avoid death. When the research team administered a combination of drugs to young rats that were aged by infusion into senescent cells, the physical capacity lost by these mice recovered between 50% and 100% in two weeks.

When the research team administered drugs to older mice between the ages of 24 and 27 months, the speed, endurance and strength of these mice increased by 30% to 100%, and their remaining life was smaller than those who did not. The mouse is 36% long. (Reporter Feng Weidong)

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