Relief drug protamine reported to emergency drug regulatory authorities for early recovery

Business Club September 14: Since the end of July this year, proteoglycans in Nanjing, Wuhan, Nantong and other places have been reported to be in emergency, and many heart surgery operations have been forced to stop. Shanghai's major hospitals may temporarily supply the amount of existing cardiac surgery. However, individual hospitals have experienced severe drug use.

Yesterday, the Shanghai Municipal Bureau of Food and Drugs disclosed that after the investigation, the drug administration department had urged the company to resume the production of protamine in advance.

The manufacturers stopped production and there were no alternatives available. "Protamine" appeared to be out of stock in many provinces and cities across the country. At present, many hospitals in Shanghai do not appear to be out of stock, but individual hospitals have also seen a tense situation. Xinhua Hospital Pharmacy Supervisor told reporters that more than a month ago, the hospital entered a lot of goods to make reserves, and now the inventory can be used for about six months to a year or so. In Eastern Hospital, inventory can also meet the daily surgical needs. However, if the amount of surgery increases, the supply of protamine will appear to be significantly strained. The use of protamine in children's hospitals has also become tense. Doctors are controlling the use of protamine in the most needed patients.

Industry insiders analyzed that since the raw material of this drug is extracted from the sperm of salmon, Shanghai manufacturers want to increase production but there are certain problems in the supply of raw materials.

It was also pointed out that the current price of a box of protamine produced in Shanghai is only 11.2 yuan, the price has remained unchanged in the past 20 years, low profits, drug companies naturally lack of production enthusiasm. In response, Shanghai Food and Drug Administration Department will investigate it at the first time. After the investigation, it was discovered that the supply of tension was not related to the cheapness of drugs but because the supply of raw materials was cut off.

Zhou Qun, head of the Safety Supervision Department of the Shanghai Food and Drug Administration, told reporters yesterday that the production of protamine that could have been restored by the end of this year and early next year is now ahead of schedule. The first batch of protamine in Shanghai First Biochemical Pharmaceutical Co., Ltd., which produces protamine, has already gone offline and can be supplied through laboratory tests. “However, it may take some time to restore the original production volume. Shanghai First Biochemical Pharmaceutical Co., Ltd. has a certain amount of reserves for this drug. However, many hospitals are currently hearing that the use of protamine is intense and they are stored in large quantities and may increase In a tense situation, the drug administration department will always follow up and urge the company to return to normal production as soon as possible and ensure the quality of supply."