Scientists develop new drug release contact lenses to treat glaucoma

Release date: 2016-09-07


Glaucoma has always been one of the common eye diseases that plague the elderly. There is currently no cure for glaucoma. Eye drops are generally used clinically to reduce intraocular pressure in patients. However, investigations have shown that patient compliance with this treatment is very low. Researchers from the Massachusetts Eye and Ear, Boston Children's Hospital, and Harvard Medical School have recently developed a drug-releaseable contact lens that promises to improve the problem.
        Researchers say that scientists have been developing contact lenses that can release drugs for more than a decade, but one of the major problems that hinders this vision is that drugs are released too quickly. Dr. Daniel Kohane, who is in charge of the study, said that in order to solve this problem, on the one hand, the researchers attached a layer of polymer film to the contact lens for absorption and sustained release of the drug. Due to its large body surface area, the rate at which the drug is released from the polymer membrane is also greatly reduced. On the other hand, the researchers vacated the center of the contact lens to keep it transparent and clean, avoiding affecting the patient's normal vision, and also ensuring the physiological indicators such as the wetness of the wearing part. This device has been validated on monkey glaucoma animal models. Researchers plan to push it to clinical research as soon as possible, which will also provide a new treatment for glaucoma patients.
        Glaucoma refers to an eye disease in which intraocular pressure is intermittent or continuously elevated. Continuous high intraocular pressure can cause damage to various tissues and visual functions of the eye. If not treated in time, the visual field can be completely lost to blindness. Glaucoma is one of the three most common blind eye diseases that cause blindness in humans. The overall population incidence rate is 1%, and after 45 years old, it is 2%. There are four main types of glaucoma: congenital glaucoma, primary glaucoma, secondary glaucoma, and mixed glaucoma.

Source: Bio Valley

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