Key words: medicinal plastic bottles, oxygen barrier, oxygen transmission rate, medicinal plastic bottles, due to their light weight, high strength, good sealing and pressure resistance, are gradually replacing medicinal glass bottles, which are widely used. The field of packaging for oral solid and liquid medicines. Oxygen is an important factor affecting the quality and safety of drugs. In order to prevent the influence of oxygen on drugs, medicinal plastic bottles should have good oxygen barrier properties to ensure product quality and safety. This article will combine Labthink's PERME OX2/230 oxygen transmission rate test system to briefly describe the oxygen transmission rate detection method for pharmaceutical plastic bottle packaging.
The oxygen transmission rate mainly refers to the barrier effect of medicinal plastic bottles on oxygen. The oxygen barrier performance directly affects the product quality of the drug during the shelf life, and is also an important factor in analyzing the shelf life. This test can solve the problem of oxidative deterioration of drugs caused by oxygen sensitivity.
Labthink OX2/230 oxygen transmission rate test system, using the isostatic method (ie coulomb method) test principle, the device comes with constant temperature and humidity control function, the whole test process computer control, automatic test, users only need to install the test After the sample, the test can be fully automated, and the test will be automatically judged and a test report will be issued.
The general test procedure is as follows: a sample of the pre-treated medicinal plastic bottle is placed in the test chamber, oxygen flows on the outside of the plastic bottle, and high-purity nitrogen flows on the inside of the plastic bottle. Oxygen molecules pass through due to the oxygen concentration gradient. The film is diffused from the outside of the plastic bottle to the inside of the high-purity nitrogen gas, carried by the flowing nitrogen to the sensor, and the oxygen concentration measured by the sensor is analyzed to calculate the oxygen permeability and other parameters to resist the test sample. Oxygen performance was evaluated.
The test schematic is as follows:
Of course, after ensuring that the oxygen barrier index of the medicinal plastic bottle package is qualified, it is necessary to control other indicators such as moisture resistance and sealing to ensure the quality of the product during the shelf life. For more information about related testing instruments, you can visit Jinan Languang for specific information or call us. Jinan Languang Electromechanical Technology Co., Ltd. is willing to enhance exchanges and cooperation with enterprises and institutions in the industry.
The oxygen transmission rate mainly refers to the barrier effect of medicinal plastic bottles on oxygen. The oxygen barrier performance directly affects the product quality of the drug during the shelf life, and is also an important factor in analyzing the shelf life. This test can solve the problem of oxidative deterioration of drugs caused by oxygen sensitivity.
Labthink OX2/230 oxygen transmission rate test system, using the isostatic method (ie coulomb method) test principle, the device comes with constant temperature and humidity control function, the whole test process computer control, automatic test, users only need to install the test After the sample, the test can be fully automated, and the test will be automatically judged and a test report will be issued.
The test schematic is as follows:
Of course, after ensuring that the oxygen barrier index of the medicinal plastic bottle package is qualified, it is necessary to control other indicators such as moisture resistance and sealing to ensure the quality of the product during the shelf life. For more information about related testing instruments, you can visit Jinan Languang for specific information or call us. Jinan Languang Electromechanical Technology Co., Ltd. is willing to enhance exchanges and cooperation with enterprises and institutions in the industry.
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