Memory of "lost" in Alzheimer's disease patients may be recovered
August 08, 2017 Source: Xinhua News Agency
Window._bd_share_config={ "common":{ "bdSnsKey":{ },"bdText":"","bdMini":"2","bdMiniList":false,"bdPic":"","bdStyle":" 0","bdSize":"16"},"share":{ }};with(document)0[(getElementsByTagName('head')[0]||body).appendChild(createElement('script')) .src='http://bdimg.share.baidu.com/static/api/js/share.js?v=89860593.js?cdnversion='+~(-new Date()/36e5)];Memory impairment is one of the main symptoms of Alzheimer's disease (also known as Alzheimer's disease). American scientists have found through animal experiments that the patient's memory information may not be really lost, but the brain's ability to read memory is problematic. .
The British "New Scientist" magazine recently reported that researchers at Columbia University in the United States used lasers to stimulate neurons to restore specific memories of rats with Alzheimer's disease. If the findings also apply to the human brain, it will be possible to develop treatments that help people find their memories.
The researchers genetically engineered the mice to make their brain neurons glow yellow when they store their memories, and red when they read them. Later, the researchers let the rats smell the smell of lemons and gave them an electric shock, which allowed them to associate the lemon flavor with the electric shock in their memory.
When the same lemon smell was heard again a week later, most healthy rats were scared of being afraid of being shocked by electric shock; while the rats suffering from Alzheimer's disease often could not remember the smell accompanied by electric shock, the experiment of being scared The mouse is much less.
It was observed that in the brain of healthy experimental mice, the neurons that emit yellow light when forming the memory of "lemon taste and electric shock" are the same batch as the neurons that emit red light in the experiment one week later. This means that when the brain reads this particular memory, it correctly finds the storage point of the information. However, in the brain of rats with Alzheimer's disease, the red-emitting neurons are another batch, indicating that the brain has found the wrong place when reading the memory.
The researchers used a blue laser to stimulate the brain of a diseased mouse to activate neurons that store yellow light when stored. The mice that have undergone this "treatment" will also be sluggish when they smell the lemon, indicating that their memories are awakened.
Since the Alzheimer's disease in the experimental mice is not completely consistent with humans, further research is needed to confirm whether the above findings are applicable to humans. In addition, the human memory mechanism is more complicated, and how to selectively restore the required memory is also a problem.
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