Yak virus diarrhea, also known as mucous membrane disease. The virus is a member of the Flaviviridae family, a member of the prion genera. The disease has a worldwide distribution, especially cattle raising more developed countries. Since 1980, China has introduced cows and cattle from more than 10 countries including West Germany, Denmark, the United States, Canada and New Zealand to introduce the disease into China. Cows, sheep, deer, and pigs can infect this disease. Diseased and poisoned animals are the main source of infection. Excreta and excreta in diseased animals are highly toxic. Rehabilitation cattle can be toxic for 6 months. The disease can be transmitted directly or indirectly, mainly through the digestive and respiratory infections, but also through the placenta infection.
In the new epidemic areas, there are more acute cases, the incidence rate is 5%, the mortality rate is as high as 90% to 100%, and the incidence of cattle is mostly 4 months to 18 months. In the old epidemic areas, there are few acute cases, and the incidence and mortality are low, while the recessive infection rate is over 50%. The incidence is higher in late winter and spring. Clinical symptoms: The incubation period was 7 days to 14 days, and most of them were latent infection. In both acute and chronic manifestations.
Sudden onset of acute disease cattle, body temperature increased 40 °C ~ 42 °C, lasted 4 days to 7 days, then decreased, and some appeared a second increase in body temperature. With the increase of body temperature, leukocytes decrease, lasting 1 to 6 days, and then the number of white blood cells will increase, and some will occur in the second reduction. The diseased animals showed mental depression, anorexia, and serous secretions in the nose and nose. During 2 days to 3 days, the surface of the nose and oral mucous membranes may be ulcerated, and the epithelium of the tongue surface was necrotic. The number of runny nose increased and the respiratory odor was increased. Severe diarrhea usually occurs after injury in the mouth, water diarrhea starts, and mucus and blood are included. Some diseased cattle have ulcerous skin necrosis of laminitis, resulting in lameness. Usually 1 to 2 weeks of death, a few cases can be delayed for one month.
In chronic cases, fever rarely occurs and body temperature fluctuates slightly. The main manifestations of endoscopic ulceration, and even into one, the eyes often have secretions; oral erosion rarely, but the incisor gums usually red; with obvious lameness; diarrhea appears uncertain. Most cases died within 2 months to 6 months.
The necropsy was performed by necropsy, dehydration, subcutaneous tissue hyperemia, nasal mucosa flushing, congestion, pneumonia, digestive tract mucosal hyperemia, and hemorrhage, especially intestinal changes. Digestive bleeding, edema, and small ulcers were observed. Mesenteric lymph node edema, increased to jujube; diffuse small intestine mucosal hyperemia, hemorrhage; cecum and colon mucosal hyperemia, hemorrhage, some ulcers; endocardial and epithelial hemorrhage; meningeal hyperemia, meningeal accumulation of a large number of edema fluid.
Prevention and treatment without special effects. Cows with elevated body temperature have been treated with antibiotics, supplemented with sugar, water, and alkali, and they ended up with death. Therefore, prevention is the key. (1) Disease-free cattle farms should strengthen the veterinary prevention and control system: (1) Adhere to the principle of self-cultivation and self-cultivation. Wherever cows are to be introduced, they should not purchase cows from the diseased area; they should first conduct serum neutralization tests on newly-purchased cattle. Reenter the court. It is forbidden to introduce diseased cows into the venue. 2 bulls and their semen can spread the disease, it should strengthen the quarantine of the bull, do not use the semen of the sick bull. Serological inspections of the entire herd are routinely conducted in order to keep abreast of the prevalence of the disease in herds. If a few bovine antibodies are found to be positive, they should be eliminated to prevent the disease from expanding. 3 The cattle farm and the cattle farm are firmly isolated, and the sick people are strictly forbidden to enter. (b) There is no specific treatment for the disease. Application of anti-diarrhea cardiac rehydration can reduce the recovery period and reduce losses. With antibiotics and sulfa drugs, secondary infections can be reduced and deaths reduced. Isolated cows in a timely manner, the following methods can be used symptomatic treatment: 1 Zhuo Ling (three cattle and sheep sheep) intramuscular injection; 2 Shu Ting Lin (a powerful cephalosporin) + five toxic through extinction + sodium bicarbonate intravenous injection. 3 high incidence of the disease can be vaccinated to prevent the disease.
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