Capillary electro-electrochemiluminescence microanalyzer was successfully developed

Release date: 2010-07-22


The Chinese Academy of Sciences Changchun Yinghua Institute completed the scientific research equipment development project of the Chinese Academy of Sciences - capillary electrophoresis electrochemiluminescence micro-integrated analyzer, recently passed the acceptance of the expert group headed by Academician Zhang Yukui in Changchun. The expert group believes that the instrument has good performance, high sensitivity and strong stability. At present, there is no such instrument at home and abroad.
It is understood that capillary electrophoresis technology and microfluidic chip analysis methods are widely used in the field of analytical science due to their high separation efficiency, good biocompatibility, and are advantageous for miniaturization and integration. attention. The organic synthesis and complementary advantages of the two are combined to develop a capillary electrophoresis electrochemiluminescence micro-integrated analyzer, which further expands its analysis object and application range, and is an important frontier in the field of international electroanalytical chemistry.
Academician Wang Erkang and researcher Xu Guobao of the Changchun Yinghua Institute of the Chinese Academy of Sciences focused on this important international frontier development direction. In February 2007, the research and development of capillary electrophoresis electrochemiluminescence micro-integrated analyzer was started with the support of the Chinese Academy of Sciences. . They pay attention to the accumulation and advantages in capillary electrophoresis detection technology and microfluidic chip analysis methods, and innovatively combine electrochemiluminescence, electrochemical and other detection technologies with analytical tools such as capillary electrophoresis and microfluidic chips. On this basis, Xi'an Ruimai Analytical Instrument Co., Ltd. cooperated to further miniaturize and integrate, and developed a prototype of capillary electrophoresis electro-luminescence micro-integrated analyzer with independent intellectual property rights in China, which is an international initiative.
At the same time, they also developed five kinds of electrochemical luminescent probes with biological application prospects in combination with the development of the analytical instrument, and applied them to biomolecule detection and analysis; a series of new methods for immobilizing electrochemiluminescent probes were established. And developed related electrochemiluminescence solid detectors. These innovations have laid an important foundation for the development of prototypes in scientific research and clinical applications.
The successful development of this instrument has enriched the research methods of basic science, and provided a new multi-functional analysis platform for scientific research in the frontier fields of protein, DNA, cell and immunity, and also provided powerful for early diagnosis and treatment of some major diseases. Support is another important and innovative achievement in the field of electroanalytical chemistry in China.

Source: Kexun

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